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Responsibilities: 

• Analyze structural computational and experimental protein data 
•  Simulate experimental and theoretical protein structures and related structural and sequence data 
• Use modeling tools to promote Amai’s computational protein design projects 
• Study structure-function-dynamics relationships 
• Communicate with fellow scientists and integrate experimental data into the design

Requirements: 

• Ph.D. in protein structural computational biophysics / computational protein design / structural bioinformatics. Excellent M.Sc. holders will also be considered. 
• Experience with computational analysis of protein structures and sequences. 
• Know-how in protein simulations, electrostatics, structure-function-dynamics relationships. 
• Know-how in mechanisms of protein folding and stabilization. 
• Proven independent scientific researcher. 
• Ability to work as part of a team and closely collaborate with others. 
• Ability to present work before colleagues and professionals. 
• Comfortable with reading and efficiently adapting new methodologies and ideas from the academic literature and other relevant publications. 

To apply, please send CV to hr@amaiproteins.com 

 Reports To: 

The Head of Downstream Processing (DSP) will report to the Director of Biotechnology. 

Job Overview: 

Receive materials from upstream processing (cells or media). Develop purification processes for different proteins expressed in different host organisms and grown with different starting materials. Prepare production documents. Scale up the process for selected proteins up to lab pilot scale. Perform tech transfer to contract manufacturing organizations (CMOs) and other collaborators. 

Purify the product to food-grade standards. Transfer the product for use by the Food Technology Department and to collaborators as part of Joint Development Agreements (JDAs), Material Transfer Agreements (MTAs) and other collaborations. 

Lead, organize, and maintain the DSP laboratory including workplans and infrastructure. Manage, guide, support, and develop the DSP team. 

Responsibilities and Duties: 

• Member of the biotech team. 
• Build and support the development and work plan. 
• Manage the DSP team:
  • Tasks 
  • Priorities 
  • Guidance and feedback 
  • HR:
    • Team welfare, and professional development. 
    • Recruiting new team members as needed. 

• Supporting and cooperating with other biotech departments:
  • USP 
  • Analytics 

Qualifications: 

• PhD in Biochemistry and related fields (MSc with very significant professional and managerial experience may be considered). 
• More than 5 years in the protein production industry 
• Fluent in Hebrew and English. 
• Background in: 
  • Protein purification process development 
  • Protein production 
  • Large scale production 

Please send CV to HR@amaiproteins.com