Help change
the world

 24/7 סטודנטים/ות למשרת משמרות

.לסטארטאפ בתחום הפודטק דרושים/ות סטודנטים/ות למשרת משמרות, כולל לילות וסופי שבוע

.מיקום: פארק המדע, רחובות

:תאור משרה

.עבודה בסיוע בפיתוח תהליכי הייצור של החברה-

.ליווי ניסויים ביחד עם צוותי המחקר בתהליכי גידול שמרים וחיידקים והפקת חלבונים-

.ביצוע בדיקות תוך כדי התהליך ואחריו-

:דרישות

.סטודנט/ית לתואר ראשון בביולוגיה/ ביוטכנולוגיה/הנדסה כימית או תחומים דומים *

.יכולת ונכונות לתפעול ציוד מעבדתי, ביצוע אנליזות ובדיקות מעבדה *

גמישות בשעות העבודה, המשרה מיועדת לעבודה של 3-4 משמרות בשבוע, כש 1-2 מתוכן משמרות לילה (המשמרות יתואמו שבוע מראש) *

.המשרה מיועדת לנשים וגברים כאחד

:תאור המשרה

ביצוע בדיקות תוך כדי תהליך ואחריו ,גידול שמרים וחיידקים והפקת חלבונים, ליווי ניסויים ביחד עם צוותי המחקר בתהליכי, עבודה בסיוע בפיתוח תהליכי הייצור של החברה

:דרישות

סטודנט/ית לתואר ראשון בביולוגיה/ביוטכנולוגיה/ הנדסה כימית או תחומים דומים *

יכולת ונכונות לתפעול ציוד מעבדתי, ביצוע אנליזות ובדיקות מעבדה *

גמישות בשעות העבודה, המשרה מיועדת לעבודה של עד שתי משמרות לילה בשבוע עם אפשרות לשינויים (המשמרות יתואמו שבוע מראש) *

המשרה מיועדת לנשים ולגברים כאחד

Job Description

• Stay abreast of technical advancements in the cloning area of microbial cell line development.
• Apply technical knowledge and expertise in cell line development (cloning, cell banking and testing, clone selection, cell line stability testing, etc.
• Collaborate with internal and external partners in fermentation and downstream process development to advance the expression and purification processes.
• Lead the molecular biology aspects within Amai’s integrated multidisciplinary R&D team on all aspects of bringing a product to the market.
• Deliver technical support to ensure successful cloning and testing the expression in small and pilot scales.
• Lead, support and manage the molecular biology team.
• Lead and support various elements of clone optimization.
• Analyze, interpret, present, and document technical information related to cloning, sequence and development data and related aspects focused on regulatory, IP, collaborative and other R&D efforts.
• Work with contract development manufacturing organizations (CDMOs) to help define project scope, review proposals, and oversee technical work, including reports’ review and approval.
• Contribute to process regulatory strategies and submissions, and quality documentation.

Requirements:

• PhD in biology, biochemistry, biochemical engineering or related field.
• A minimum of two years’ experience of relevant process development for protein production.

Experience with clone optimization and selection, in various organisms.

• Demonstrated capability to work independently on complex technical problems and, in parallel, demonstrated capability of working effectively in cross-functional teams, and with external CDMOs and partners.
• Experience planning, generating, analyzing, and linking experimental capabilities and results to critical USP objectives.

Knowledge/Skills:

• • Expertise in molecular biology and cloning into bacteria and eucarya.
  • Knowledge of CMC biologics upstream processes.
  • Working knowledge of proteins’ microbial cell line development workflows.
  • Ability to apply technical knowledge to clone development and banking across the product life cycle.
  • Ability to collaborate with and lead effectively cross-functionally and in a team setting, both internally and with external CDMOs and partners.
  • Ability to multi-task in a fast-paced dynamic environment while delivering high quality work.
  • Sets goals with understanding of priority and impact to the program, department, and organization.
  • Creative thinker and complex problem solver.
  • Must have outstanding interpersonal relations and team working capabilities.

Responsibilities:

• Analyze sequence and structural computational and experimental data of proteins, RNA and DNA.
• Develop software tools for efficient data integration and mining
• Conduct literature and patent searches
• Collaborate with other departments
• Curate and manage of in-house datasets
• Develop and maintain in-house pipelines of analysis, implementing best coding practices
• Communicate with fellow scientists and IT experts

Requirements:

• M.Sc. in bioinformatics / computational biology / computational biophysics. Experienced excellent B.Sc. holders will also be considered
• Experience with computational analysis of protein and nucleic acid data
• Proven programming experience in Python (experience with GitHub is an advantage)
• Proven experience in Unix/Linux ecosystems
• Ability to mentor scientists from other disciplines on computational and bioinformatics solutions, advancing in-house collaboration and data sharing
• Ability to work as part of a team and closely collaborate with others

As bioanalytical manager you will manage, give technical leadership and support the bioanalytical team. You will design, manage, validate, execute, and analyze results related to the analysis of samples from R&D and production processes. You will also work with many service providers and will be signing the product CoA. The position entails hands-on laboratory work.

Description:

• Stay abreast of technical advancements in the analytical area of proteins and new alternative food.
• Apply technical knowledge and expertise in protein analysis (chromatography, bioassays, chemical analysis, biochemistry, etc.)
• Collaborate with internal groups and departments as well as with external partners.
• Deliver technical support to ensure successful analytical methods development, validation and execution.
• Lead and support various elements of analytical process development.
• Analyze, interpret, present, and document technical information and release results to the different teams.
• Work with local and international service providers to analyze the samples and release of final product (CoA).
• Contribute to process regulatory strategies and submissions, and quality documentation.

Requirements:

• PhD in chemistry, biology, biochemistry or related field.
• A minimum of five years’ experience of relevant analytical development for proteins production.

Highly experienced with analytical methods of protein analysis, e.g. HPLC.

• Demonstrated capability to work independently on complex technical problems, effectively in cross-functional teams, and with external service providers and partners.
• Experience planning, generating, analyzing, and linking experimental capabilities and results to critical USP objectives.

Knowledge/Skills:

• Expertise in protein analysis by different methods.
• Knowledge of CMC biologics processes.
• Working knowledge in chemical, biochemical, bioassays and physical analysis of proteins.
• Experience in analytical process validation and SOP preparation.
• Ability to collaborate with and lead effectively cross-functionally in a team setting, both internally and with external service providers.
• Ability to multitask in a fast-paced dynamic environment while delivering high quality work.
• Goal setting with understanding of priority and impact to the program, department, and organization.
• Creative thinker and complex problem solver.
• Must have outstanding interpersonal relations and team working capabilities.