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If you’re interested in joining us, please send your CV and cover letter to hr@amaiproteins.com

A Computational Structural Protein Designer

Description

Responsibilities: 

  • Analyze structural computational and experimental protein data 
  •  Simulate experimental and theoretical protein structures and related structural and sequence data 
  • Use modeling tools to promote Amai’s computational protein design projects 
  • Study structure-function-dynamics relationships 
  • Communicate with fellow scientists and integrate experimental data into the design

 

Requirements: 

  • Ph.D. in protein structural computational biophysics / computational protein design / structural bioinformatics. Excellent M.Sc. holders will also be considered. 
  • Experience with computational analysis of protein structures and sequences. 
  • Know-how in protein simulations, electrostatics, structure-function-dynamics relationships. 
  • Know-how in mechanisms of protein folding and stabilization. 
  • Proven independent scientific researcher. 
  • Ability to work as part of a team and closely collaborate with others. 
  • Ability to present work before colleagues and professionals. 
  • Comfortable with reading and efficiently adapting new methodologies and ideas from the academic literature and other relevant publications. 

 

To apply, please send CV to hr@amaiproteins.com 

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A Computational Structural Protein Designer

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Head of Protein Downstream Processing

Description

 Reports To: 

The Head of Downstream Processing (DSP) will report to the Director of Biotechnology. 

Job Overview: 

Receive materials from upstream processing (cells or media). Develop purification processes for different proteins expressed in different host organisms and grown with different starting materials. Prepare production documents. Scale up the process for selected proteins up to lab pilot scale. Perform tech transfer to contract manufacturing organizations (CMOs) and other collaborators. 

Purify the product to food-grade standards. Transfer the product for use by the Food Technology Department and to collaborators as part of Joint Development Agreements (JDAs), Material Transfer Agreements (MTAs) and other collaborations. 

Lead, organize, and maintain the DSP laboratory including workplans and infrastructure. Manage, guide, support, and develop the DSP team. 

Responsibilities and Duties: 

  • Member of the biotech team. 
  • Build and support the development and work plan. 
  • Manage the DSP team:
    • Tasks 
    • Priorities 
    • Guidance and feedback 
    • HR:
      • Team welfare, and professional development. 
      • Recruiting new team members as needed. 
  • Supporting and cooperating with other biotech departments:
    • USP 
    • Analytics 

Qualifications: 

  • PhD in Biochemistry and related fields (MSc with very significant professional and managerial experience may be considered). 
  • More than 5 years in the protein production industry 
  • Fluent in Hebrew and English. 
  • Background in: 
    • Protein purification process development 
    • Protein production 
    • Large scale production 

Please send CV to HR@amaiproteins.com 

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Head of Protein Downstream Processing

Research assistant for molecular biology & cloning

Description

Reports To:

The employee will report to the manager of the molecular biology and cloning lab and to the Director of Biotechnology.

Job Overview

Cloning work and expression screening of host organisms. Small-scale production of novel designer proteins for preliminary analysis. Microorganism (glycerol) stock maintenance. Preparation of production documents. Transfer and support for the scaleup team. Small-scale downstream protein purification up to food-grade standards to be used by the Food Technology Department. Support of any additional ongoing projects in the lab.

Responsibilities and Duties:

  • Member of the biotech team.
  • Ability to learn quickly and work independently.
  • Supporting and cooperating with other units and departments:
  • Computational protein design
  • Fermentation
  • Analytics
  • Food technology

 

Qualifications:

  • BSc in Biochemistry and/or related fields (experience in lab research is a big plus).
  • Experience in molecular biology and cloning – advantage
  • Background in protein purification or HPLC – advantage
  • Fluent in Hebrew and English.
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Research assistant for molecular biology & cloning

24/7 סטודנטים /ות למשרת משמרות

Description

:תאור המשרה

ביצוע בדיקות תוך כדי תהליך ואחריו ,גידול שמרים וחיידקים והפקת חלבונים, ליווי ניסויים ביחד עם צוותי המחקר בתהליכי, עבודה בסיוע בפיתוח תהליכי הייצור של החברה

:דרישות

סטודנט/ית לתואר ראשון בביולוגיה/ביוטכנולוגיה/ הנדסה כימית או תחומים דומים *

יכולת ונכונות לתפעול ציוד מעבדתי, ביצוע אנליזות ובדיקות מעבדה *

גמישות בשעות העבודה, המשרה מיועדת לעבודה של עד שתי משמרות לילה בשבוע עם אפשרות לשינויים (המשמרות יתואמו שבוע מראש) *

המשרה מיועדת לנשים ולגברים כאחד

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24/7 סטודנטים /ות למשרת משמרות

Computational Biologist & Informatician

Description

Responsibilities:

· Analyze sequence and structural computational and experimental data of proteins, RNA and DNA.

· Develop software tools for efficient data integration and mining

· Conduct literature and patent searches

· Collaborate with other departments

· Curate and manage in-house datasets

· Develop and maintain in-house pipelines of analysis, implementing best coding practices

· Communicate with fellow scientists and IT experts

 

Requirements:

  • M.Sc. in bioinformatics / computer science / computational biology / computational biophysics. Experienced excellent B.Sc. holders will also be considered
  • Experience with computational analysis of protein and nucleic acid data
  • Proven programming experience in Python (experience with Github is an advantage)
  • Proven experience in Unix/Linux ecosystems
  • Ability to mentor scientists from other disciplines on computational and bioinformatics solutions, advancing in-house collaboration and data sharing
  • Ability to work as part of a team and closely collaborate with others
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Computational Biologist & Informatician

Food Technologist

Description

Job Description

  • Testing and implementing Amai ingredients in a variety of food and beverage applications
  • Preparing samples for internal testing (coding, serving)
  • Managing samples
  • Conducting shelf-life studies
  • Inventory management and ordering raw materials, and equipment (internally and externally).
  • Data management: in-house data management and external data mining.
  • Participating in team meetings
  • Performing basic statistical calculations on results

Food technologist Requirements:

  • B.A., B.Sc. in food science (this job opening is not relevant for Nutritionists and Dietitians )
  • Good technical abilities
  • No need for experience ( can be right after university )
  • Well-articulated in Hebrew and English. Other languages – advantage
  • Computer – Office applications use. Statistical software – advantage
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Food Technologist

Fermentation Research Associate

Description

Responsibilities:

  • Fermentation Process Development: Design, plan, and conduct experiments to develop and optimize fermentation processes to produce various proteins via different host microorganisms.
  • Support of the Molecular Biology team with strain screening and selection.
  • Process Monitoring and Control: Implement strategies for real-time monitoring and control of fermentation processes.
  • Data Analysis and Reporting: Analyze experimental data. Summarize findings in technical reports and presentations to share progress and results.
  • Equipment Maintenance: Oversee the maintenance and calibration of fermentation equipment, ensuring that they are in optimal working condition.
  • Writing working procedures and SOP’s.

 

Qualification and skills:

  • BSc. In life science/chemical engineering/biotechnology engineering.
  • At least two years of experience in lab fermentation, a strong knowledge of fermentation principles.
  • Knowledge of various fermentation technologies, bioreactors, and control systems.
  • Excellent problem-solving skills and the ability to troubleshoot fermentation-related issues.
  • Good communication and teamwork skills to collaborate effectively with interdisciplinary teams.
  • Strong attention to detail and a commitment to maintaining a safe laboratory environment.
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Fermentation Research Associate

Head of Upstream Process (USP) Development

Description

Reports to: Director of Biotechnology

Job description:

  • Stay abreast of technical advancements in the USP area of microbial cell line development and fermentation process development.
  • Apply technical knowledge and expertise in cell line development (cloning, cell banking, and testing, clone selection, cell line stability testing, etc), upstream process development (fermenters design, media, and feed optimization, etc), and technology transfer to the pilot group and to different CMOs.
  • Support transfer, development, and scale-up of microbial fermentation process technology from research into process development and scale-up to enable production.
  • Collaborate with internal and external partners in downstream process development, analytical development, and pilot groups to advance CMC biologics programs.
  • Deliver technical support to ensure successful small and pilot production, and to develop and implement process improvements as programs advance.
  • Lead and support early-stage upstream process development activities.
  • Analyze, interpret, present, and document the technical information such as cloning, sequence, and development data, in support of regulation objectives.
  • Work with international contract development manufacturing organizations (CDMOs) to help define project scope, review proposals, and oversee technical work, including reports’ review and approval.
  • Contribute to process regulatory strategies and submissions, and quality documentation.
  • Work to establish, maintain, and lead internal upstream process development.
  • Contribute to the preparation of grant applications and reports as well as workplans, KPIs, and reports to the management.

Requirements:

  • PhD in biology, biochemistry, biochemical engineering, or related field.
  • A minimum of five years’ experience in relevant process development for protein production.
  • Experience with clone selection, fermentation process optimization in various formats, and process scale-up.
  • Demonstrated capability to work independently on complex technical problems, effectively in cross-functional teams, and with external CDMOs and partners.
  • Experience in planning, generating, analyzing, and linking experimental capabilities and results to critical USP objectives.

Knowledge/Skills:

  • Expertise in upstream process development
  • Broad and deep knowledge of CMC biologics upstream processes.
  • Working knowledge of proteins’ microbial cell line development workflows.
  • Ability to apply technical knowledge to development and manufacturing for biologics across the product life cycle.
  • Ability to collaborate with and lead effectively cross-functionally and in a team setting, both internally and with external CDMOs and partners.
  • Ability to multi-task in a fast-paced dynamic environment while delivering high-quality work.
  • Set goals with an understanding of priority and impact on the program, department, and organization.
  • Creative thinker and complex problem solver.
  • Must have outstanding interpersonal relations and team working capabilities.
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Head of Upstream Process (USP) Development

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